All Deadpool wants out of life is death - but because of his incredible healing factor, it's the one final mark that has eluded him. When a friend gives him a serum that permanently disables his regenerative abilities, Deadpool is faced with mortality for the first time. But when his newfound ability to die makes Deadpool feel more alive than ever, his sudden lust for life gets him in hot water with a pair of merciless crime bosses, a team of super villains, his fellow mercenaries and a dual-Beretta-wielding monkey with a chip on his shoulder. Can the Merc with a Mouth escape his pursuers and his pattern of insanity-fueled self-destruction and finally live life to the fullest? Featuring Uncanny X-Force, Daken, the Kingpin, the Intelligencia, Hit-Monkey and many more!COLLECTING: Deadpool 50-63