Numerous studies have documented the importance of diastolic dysfunction in heart disease. Now, providing cardiologists with current information available on the subject, the editors have pooled contributions from an array of researchers and compiled them into one comprehensive source. This edition, based on a recent meeting, includes such topics as: molecular biology of relaxation; consequences of altered gene expression; impaired relaxation in experimental models (ischaemia and hypoxia, and hypertrophy and failure); diastolic dysfunction in the diseased human heart. This work should be of use to practising cardiologists and scientists researching the effects of diastole on heart function.