Fields of white opium poppies stretch away over the hills, and uniformed workers bend over the rows, harvesting the juice. This is the empire of Matteo Alacran, a feudal drug lord in the country of Opium, which lies between the United States and Aztlan, formerly Mexico. Field work, or any menial tasks, are done by "eejits," humans in whose brains computer chips have been installed to insure docility. Alacran, or El Patron, has lived 140 years with the help of transplants from a series of clones, a common practice among rich men in this world. The intelligence of clones is usually destroyed at birth, but Matt, the latest of Alacran's doubles, has been spared because he belongs to El Patron. He grows up in the family's mansion, alternately caged and despised as an animal and pampered and educated as El Patron's favorite. Gradually he realizes the fate that is in store for him, and with the help of Tam Lin, his bluff and kind Scottish bodyguard, he escapes to Aztlan. There he and other "lost children" are trapped in a more subtle kind of slavery before Matt can return to Opium to take his rightful place and transform his country. Matteo Alacrán was not born; he was harvested. His DNA came from El Patrón, lord of a country called Opium--a strip of poppy fields lying between the United States and what was once called Mexico. Matt's first cell split and divided inside a petri dish. Then he was placed in the womb of a cow, where he continued the miraculous journey from embryo to fetus to baby. He is a boy now, but most consider him a monster--except for El Patrón. El Patrón loves Matt as he loves himself, because Matt is himself.
As Matt struggles to understand his existence, he is threatened by a sinister cast of characters, including El Patrón's power-hungry family, and he is surrounded by a dangerous army of bodyguards. Escape is the only chance Matt has to survive. But escape from the Alacrán Estate is no guarantee of freedom, because Matt is marked by his difference in ways he doesn't even suspect.