New York City Homocide Detective Jon Christopher has a perfect record bringing serial killers to justice, but now all that has changed: the genocidal maniac dubbed the Pale Saint has eluded him for 18 months. When Christopher's best friend, assistant DA Bobby Austin, becomes the Pale Saint's latest victim, Christopher's need to catch the killer becomes a matter of personal obsession.
Forced to take desperate measures in order to track down the Pale Saint, Christopher enlists an unexpected partner, the great lost love of his life, Austin's widow, Cassandra, a brilliant genetic engineer. Together they make a cataclysmic decision: they will create and train a clone of the Pale Saint, his mirror image, to become the human bullet that will bring the wily killer down.