Two hundred years from now, blood has become the most valuable commodity on the planet-especially the blood of aboriginal peoples, for it contains antibodies that protect them from the Plague ravaging the rest of the world.
Sixteen-year-old Cassandra Mercredi might be immune to the Plague, but that doesn't mean she's safe-government forces are searching for those of aboriginal heritage to harvest their blood. When a search threatens Cassandra and her family, they flee to the Island: a mysterious and idyllic territory protected by the Band, a group of guerilla warriors-and by an enigmatic energy barrier that keeps outsiders out and the spirit world in. And though the village healer has taken her under her wing, and the tribal leader's son into his heart, the creatures of the spirit world are angry, and they have chosen Cassandra to be their voice and instrument...