When Detective Lawrence Ribaud wakes alone in a bloody bed with his wife missing, he knows this is more than just a mysterious case of murder. His wife is the latest victim in a string of bizarre disappearances. All across New Orleans, on one night each month, people are vanishing, leaving behind nothing but a pool of blood on the bedsheets... and an abandoned heart. Ribaud doesn't believe in voodoo, but he soon finds himself moving through the underbelly of a secret society of snakes, sacrifices and obscene rituals in search of the mysterious Black Queen... and the curse of her Voodoo Heart.